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Why do we feel sick ?

The immune system and the central nervous system are two seemingly separate bodily systems that have long been studied independently. Yet, when the immune system is activated by infection or inflammation, the brain orchestrates a set of sickness symptoms thought to improve survival, such as fever, anorexia, lethargy and more. 

The goal of the Osterhout lab is to understand why and how an systemic infection makes us feel sick 

We utilize cutting-edge approaches for behavioral characterization, viral-mediated functional manipulation and single-cell gene expression analyses to better understand the principles governing immune-brain communication and how sickness symptoms are generated

Where to find us

Our lab is part of the thriving neuroscience community at the University of Utah. We are part of the Neurobiology Department in the School of Medicine and affiliated with the Neuroscience and the Bioscience PhD programs. Our lab is involved in culture and community outreach efforts on campus and the greater Salt Lake Valley.

News

7/1/24

Osterhout Lab awarded the Klingenstein-Simons Fellowship

6/3/24

Michelle Swarovski awarded the Neurimmunology T32 fellowship

Congrats Michelle!

5/16/24

Hailee Walker joins the lab

Hailee joins the lab as a co-advised student with Nick Frost. Welcome!

5/15/24

Osterhout Lab awarded the Whitehall Research Grant

1/22/24

Danielle Germundson-Hermanson joins the lab as our first postdoc

Welcome Danielle!

Press

Jessica interviewed for Stories of Women in Neuro (WiN)

Stories of WiN features profiles of women in neuroscience. 

Your brain could be controlling how you get sick

A news feature in Nature describes how scientists are deciphering communication in the brain during immune responses, hoping to find treatments for a range of diseases

Open Box Science

See Jessica present her work on the generation of fever and sickness behaviors on Open Box Science!

Brain Explained

Jessica featured on the Brain Explained podcast

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